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In the REDEFINE 1 trial, 60% of participants receiving once-weekly CagriSema (cagrilintidesemaglutide) achieved at least 20% weight loss, and 23% lost 30% or more, which is among the most significant results seen with any anti-obesity medication to date
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(2012) demonstrated that It could improve cognitive function in models of Alzheimers disease by promoting neuronal repair and synapse formation, suggesting its potential as a therapeutic for neurodegenerative conditions

Hepatic function similarly has minimal impact on tirzepatide clearance