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Food and Drug Administration (FDA) approved cenobamate tablets (Xcopri, SK Life Science Inc.) as a new treatment option for partial onset seizures in adults, based on two randomized controlled trials that established safety and efficacy

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Many anticonvulsant drugs act by increasing GABA in the synapse.[ref] Genetic variants that decrease the function of the GABA-A receptors essentially decreasing GABA inhibition are linked to an increased risk of epileptic seizures.[ref] Insomnia: Brain GABA levels were studied in people with primary insomnia who were not on medication

Cell 51 , 887898 (1987)