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Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

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The rRV1954A protein (10 g/ml) was treated with Proteinase K (PK) to serve also as a control

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Second, direct inhibitory effects of cytokines: When the levels of pro-inflammatory cytokines (represented by TNF-) in seminal plasma rise to a certain threshold, they can exert direct toxic inhibition on sperm, manifested as declines in sperm vitality and progressive motility

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