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It only takes days to progress, and it is worsening over a day or two or three so that gets you a week or so plus/minus, outside maybe 2 weeks, Kaufman explains
After B12 injections, his symptoms dramatically improved

Phase 2: Days 16-30 (2 mg/day) From day 16 onward, the dose doubles to 8 units (2 mg per injection)

Energy Homeostasis Models : A robust tool for observing shifts in basal metabolic rate and cellular energy expenditure
