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Description
He described daily episodes during which he would sit in a chair and lose hours being "busy in mind." He was started on treatment with sertraline 50 mg, which was titrated to 150 mg over 1 month, and prazosin 1 mg titrated to 4 mg over 2.5 months

In addition to genetic testing, plasma folate and homocysteine levels can be measured to assess the impact of MTHFR gene mutations on folate metabolism
Dosing, timing, and potential interactions all need consideration

& Cherrington, A
