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For insulin delivery into the brain, transplanting islets into the cranial subarachnoid cavity was often exploited

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Fatigue is associated with inflammatory markers IL6, tumor necrosis factor (TNF) and C-reactive protein (Bryleva et al

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1 (2023): 112, 10.1186/s12883-023-03284-6

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This mechanism produces the hallmark finding of a fractional excretion of calcium of less than 1%, which definitively distinguishes this benign condition from other causes of hypercalcemia

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