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The ratio of reduced to oxidized glutathione (GSH/GSSG) is often used as a factor to assess cellular antioxidant capacity or cytotoxicity ( Although bullfrogs have been cultured in captivity for a long time, there is a gap in the study of bullfrog diseases, especially the study of hepatic lipid metabolism part

Detoxification and Its Impact on Longevity Glutathione is also vital in the detoxification process, helping the body eliminate harmful substances such as heavy metals and chemicals

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Besides, berberine can prevent NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome from being activated during the inflammation process of Parkinsons disease and restore autophagy activity to protect dopamine neurons ( In addition to the above studies, in the zebrafish Parkinsons disease model, berberine derivatives can be used to treat Parkinsons disease