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doi: 10.1016/bs.pmbts.2016.09.008 218 LingJKangYZhaoRXiaQLeeDFChangZet al

Design of a backbone rat amylin(2737) peptide with micromolar affinity for amylin receptor ECDs The amylin receptor has the extracellular domain (ECD) where a peptide ligand binds presumably at the initial stage of amylin receptor interaction

Random timing wastes efficacy

Alpha-1 antitrypsin inhibits ATP-mediated release of interleukin-1beta via CD36 and nicotinic acetylcholine receptors