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Chitosan and its derivatives have also demonstrated significant advantages in nasal drug delivery by enhancing residence time through strong mucoadhesion while simultaneously promoting epithelial interaction and transient opening of tight junctions, thereby facilitating drug absorption without relying solely on high bulk viscosity (Casettari and Illum, 2014)

For quantitative analyses, 1 fmol of p 7 /soto-p 7 and 5 fmol of p 8 /soto-p 8 were spiked into cell lysates prior to immunoprecipitation

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Alvarez FJ, Lafuente H, Rey-Santano MC, Mielgo VE, Gastiasoro E, Rueda M, et al