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2) This study performed by researchers Heffernan et al explored the chronic and acute metabolic effects of AOD9604 in several mouse models, including lean C57BL/6J, ob/ob, WT, and 3-KO mice

On top of Vitamin B12 and Folic Acid, methylation cycling is supported by Choline and Vitamin B6

A recent overview article summarizing AOD 9604 research notes that in isolated chondrocyte cultures, AOD 9604 has been reported to promote proteoglycan and collagen production , and may influence differentiation of adipose-derived mesenchymal stem cells toward osteogenic lineages suggesting a possible role as a tool to study cartilage and bone matrix biology
