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Additionally, they lead to the activation of several intracellular protective pathways [132,133,134]

This is the inflammatory response that, usually within a few weeks or months of the pain starting, produces a scar that can be palpated in the flaccid penis

Discontinue use if irritation or rash develops and consult a physician

Tretinoin causes retinoid dermatitis (redness, peeling, dryness) in most new users
