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The study was conducted in accordance with the protocol and the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) Good Clinical Practice (GCP) guidelines, Declaration of Helsinki and applicable Swiss and European Union regulations
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Beyond anaphylaxis, the extract effectively reduced scratching behavior induced by platelet-activating factor (PAF), serotonin (5-HT), and proteases without central depressant effects (Ueda et al
