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Available from: 3 Committee discussion | Autologous chondrocyte implantation for treating symptomatic articular cartilage defects of the knee | Guidance | NICE [Internet]

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Metabolomics data further show coordinated rhythmic shifts in amino acids, B-vitamins, and lipid species across phases, which may reflect windows of greater metabolic vulnerability in which nutritional inadequacy, low energy availability, or high training loads may more readily precipitate symptoms or performance decrements [3]

Inadequate protein during rapid fat loss leads to lean mass loss alongside fat loss, reducing the quality of the final body composition result