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Description
IsoalloLCA, a lithocholic acid (LCA) derivative, enhances peripheral Treg (pTreg) differentiation via FoxP3 upregulation in a TGF- and CNS3-dependent manner through mitochondrial Reactive Oxygen Species (ROS), independent of the Vitamin D Receptor (VDR) (70)
However, VIPRs are highly overexpressed in the majority of human tumors and are particularly common in frequently occurring cancers
Reduces fine lines
C.et al (2011)
