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doi: 10.1210/jcem.82.1.3688

40 Clinical trials have found polyphenols from cocoa increase nitric oxide production and support healthy endothelial function, decrease inflammatory marker levels, reduce oxidative damage to lipids, and promote growth of beneficial bacteria in the gut

A later prospective controlled study also revealed a strong correlation between IR and the inflammatory state in PCOS patients (Hotamisligil et al., 1994

Genetic factors Asthma is clearly caused by the combination of environmental factors and genetic factors that significantly contribute to the individual's asthma predisposition [42] and which may influence endotypes of asthma [43]
