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Description
Neurodegenerative diseases are characterized by progressive neuron losses in specific brain regions that impact cognitive, sensory, and motor functioning

As such, elevated plasma 27-OHC has been associated with major depressive disorder as a result of impaired serotonin signaling, hypothalamicpituitaryadrenal (HPA) axis dysregulation and hippocampal neurotoxicity (Daray et al., 2018
10.3390/ph16111596 106 PritchardD.PatelJ

Zinc ions compete with copper for certain cellular pathways
