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As a consequence, it could not be enough to target only one of these factors, but a combination of therapeutic approaches with different targets could be more powerful
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Besides the activation of the opioid system, morphine-analgesia encompasses many other neurotransmitter systems, and different peptides (1-5)
Functionally, SB-216763 reduced 1A -AR desensitization due to oxymetazoline but augmented PMA-induced desensitization
