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3.2.1 Hirudin Hirudin is a primary active component derived from the medicinal leech ( Hirudo medicinalis Linnaeus, belonging to the Hirudinidae family), exhibiting anticoagulant, antifibrotic, antithrombotic, and anti-inflammatory properties, and demonstrating significant protective effects on the kidneys ( Initially, in the realm of metabolic regulation, research has demonstrated that hirudin can lower blood sugar levels and glycated hemoglobin in a rat model of DKD induced by a high-fat, high-sugar diet combined with streptozotocin (STZ)

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Case Studies and Evidence: Recent research and clinical studies have highlighted the effectiveness of BPC-157 in treating joint pain (Parks et al., 2022)

This results in tumor cells expressing higher levels of MTH1 compared to normal cells