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27 CLINICAL USE The first studies of acetylcysteine therapy involved patients who presented to a health care facility within 24 hours after a single acute ingestion of acetaminophen and had a plasma concentration above the study line (also known as the possible toxicity line) on the RumackMatthew nomogram (Fig

The variations in APX, MDHAR, DHAR, GR, gamma-glutamylcysteine synthetase (-ECS), and glutamate-ligase (GaILDH) levels were in line with gene expression upregulation

GL: Writing review and editing, Investigation, Conceptualization, Formal Analysis, Writing original draft
