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For instance, acetylation, O-GlcNAcylation, and ubiquitination have been shown to be involved in insulin gene transcription, and phosphorylation has a role in mediating the signaling cascades needed for insulin secretion (83)

First, growth hormones fat-mobilizing effect is coupled, in the intact hormone, to metabolically costly side effects: the same signaling that liberates fatty acids also raises circulating IGF-1 and can worsen insulin sensitivity, which is precisely why chronic growth-hormone administration is not a benign way to lose fat

[45] Greger also serves in the U.S