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excess body weight itself drives insulin resistance
GC7 decreased the nascent HIF-1 protein level, as assessed by measuring the abundance of newly synthesized HIF-1 proteins labeled with L-azidohomoalaine (AHA) in the presence or absence of GC7 (Fig

The primary routes for permeation across the BBBinclude passive diffusion (lipid soluble solutes), ABC transporter efflux, carrier-mediated influx, and receptor-mediated transcytosis (Pandian et al., 2022