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Description
These observations are likely related to the reversal of the previously observed immunomodulation by the parasite

Targeted interventions (both nonpharmacologic [eg, motivational interviewing, 12-step programs, and cognitive-behavioral therapy] and pharmacologic [eg, disulfiram, naltrexone, acamprosate, topiramate, and gabapentin]) are available to mitigate the risks of excessive alcohol use and prevent their associated morbidity and mortality

This model provides direct oversight, not contracted or third-party medical direction
The Post-translational Modification, SUMOylation, and Cancer (Review)
