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The blood pressure-concentration plot presented clockwise hysteresis, similar to the subjective drug effect-concentration plots, indicating acute pharmacological tolerance ( Supplementary Figure S5 )

Weather Rev., 139, 38873905, 2011

doi: 10.1152/ajpcell.00139.2004 56 Vander HeidenMGCantleyLCThompsonCB

On the regulated market there are drugs and medicinal interventions with far worse known side effects and complications
