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Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant tumors with limited treatment options, and chemotherapy resistance contributes to poor prognosis

A B12 deficiency can result in entirely blue nails, bluish-black pigments with wavy longitudinal dark streaks, and brownish pigmentation

If it impacts the testicular microenvironment, it could enhance sperm count or motility, but data are limited and the mechanism is different than how it might act in ovaries or endometrium

doi: 10.1210/jc.2016-1896
