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S -(3-hydroxypropyl)- N -acetylcysteine) Keap1 Kelch-like ECH-associated protein 1 LDL low-density lipoprotein MPO myeloperoxidase NF-B nuclear factor-B Nrf2 nuclear erythroid-2 related factor 2 OPMA S -(3-oxopropyl)mercapturic acid (syn

Methods for detecting off-target effects of CRISPR/Cas9

Glutathione is considered to be one of the body's most powerful antioxidants, involved in a number of enzyme systems necessary for detoxification, the neutralization of free radicals, and maintaining blood-brain barrier function

While we did not evaluate the tight junctions in this study, our results support that changes in astrocyte morphology are sufficient to induce changes in bloodbrain barrier permeability