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Description
22Rv1 cells) treatment significant reduction of downstream phosphorylation of RNA Pol II at Ser2 and Ser7, and diminished phosphorylation at Ser5
Thus, finally leads to the polyubiquitylation of HIF-1 and its proteasomal degradation by the 26S subunit
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Activation of XKR8 by caspase-3 triggers NET formation The signaling cascades that orchestrate NET formation are extremely intricate and not yet fully understood 15,26
