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A small clinical trial (N = 82 LOE 1b) in 2013 showed that LC supplementation improved disease indicators and nutritional status in ALS patients with daily supplementation of 1000 mg LC in 40 patients aged 40 to 75 years, while the control group was still given the same amount of placebo [21]

One previous study showed that overexpression of the pls gene using the kasOp* promoter and ribosome binding site from phage C31 capsid protein in a modified S

Next, targets in the PPI network was analyzed using MCODE revealed six clusters (Figure 3C

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