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In accordance, it was previously shown that BSO can re-sensitize ABCC1 -overexpressing cells to Etoposide and Daunorubicin 80

Indeed, mice heterozygous for Mclk1 (a mitochondrial hydroxylase necessary for ubiquinone synthesis) display increased mitochondrial ROS with elevated normal innate and adaptive inflammatory responses to fight pathogens without incurring tissue damage [100]
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