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Although these results provide a compelling case for nitrate supplementation to improve aspects of endurance performance, it is important to note that there is not unanimous agreement on these conclusions

This logic has limits

Pre-medication with a bronchodilator may be recommended in such cases.

Absorption problems Even with adequate intake, absorption can be reduced by: Certain gastrointestinal conditions affecting the stomach or small intestine Some medications Age-related reduction in stomach acid (which can affect absorption) Autoimmune gastritis (often historically referred to as pernicious anaemia) This is a well-recognised cause of B12 deficiency and may require ongoing management