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Chimeric antigen receptor (CAR) T-cell exhaustion within the bone marrow microenvironment is driven by nutrient deprivation, hypoxia, and accumulation of immunosuppressive metabolites
doi:10.4103/0028-3886.314574
Resistance to Chemotherapy is Associated With Altered Glucose Metabolism in Acute Myeloid Leukemia
In addition, proteomic analysis confirmed upregulation of collagen type I and decorin, consistent with dermal remodeling activity
