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This shift leads to decreased liver inflammation and injury in sepsis-induced acute hepatic damage models, alongside reduced TLR4 expression and inflammatory markers [165]

10.1016/j.tjnut.2024.03.001 100 LuoD.HuangZ.JiaG.ZhaoH.LiuG.ChenX
A prospective cohort study of neuropsychological test performance in ALS
This means most of a high-dose supplement remains in the gastrointestinal tract, though the direct link to digestive symptoms is not well established