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Stereological and histological studies exhibited that, after busulfan treatment, some large vacuoles were observed in the seminiferous tubules in the rat testis and the size of seminiferous tubules was reduced, which was linked to disorganization and reduction of height of germinal epithelium following depletion of spermatogenic lineage cells (spermatogonia, spermatocytes, and round elongated spermatid)

However, it is always recommended to seek advice from a doctor before starting any new supplement regimen

Several studies have shown that supplementing with L-carnitine can diminish the above symptoms in adult dialysis patients, but whether children can benefit from L-carnitine remains unclear