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Patients may also have low levels of vitamin B12 if they have had bariatric surgery, are strict vegetarians, or have used antacids or proton pump inhibitors for a prolonged period

Semax is also known for its role in mitigating hypoxia-induced effects on brain tissue, making it relevant to research on ischemic brain injury and conditions involving reduced cerebral blood flow

The extraction was conducted using a supercritical fluid extractor under optimal extraction conditions in the industrial process, which the Chao Phraya Abhaibhubejhr Hospital Foundation carried out