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Description
These peptides activate MRGPRX2, a mast-cell receptor that fires on positively charged, aromatic molecules and releases histamine into the tissue. Sodium and chloride ions screen the peptides positive charge, so the receptor sees less of it and the welt shrinks

Alcohol can increase bruising and interfere with the body's inflammatory response

2019 Apr 26;12:1341-1351
F.DeBoldJ