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Skin lesions induced by immune checkpoint inhibitors Immunomodulatory therapies with immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, but their use is associated with the occurrence of immune-mediated AEs, with skin toxicity being the most frequent

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Vincent Canby reviewed the film negatively, and was critical of De Niro's casting: "De Niro, who was very fine as the street-wise priest in True Confessions , is all right here until he opens his mouth." [77] However, the film won an Academy Award for Best Cinematography, three BAFTAs, including Best Editing, and two Golden Globes for Best Screenplay and Best Original Score