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Furthermore, quantitative real-time PCR (qPCR) analysis of melanoma oncogenic genes (CD271, NES, AXL, LOXL2, MITF, MELANA, SOX10) and the melanoma chemotactic gene, CCL2, showed significant downregulation and a change in downstream signalling of these genes by glutamine supplementation in both PDX tumour models (Fig

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To assess the link between GLP-1 and angiotensin receptor type 1 (AT1) signaling on obesity-associated impairment of urinary Na+ excretion (UNaV) and elevated a

Kukoamine a protects mice against osteoarthritis by inhibiting chondrocyte inflammation and ferroptosis via sirt1/gpx4 signaling pathway
