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80 , 81 Lysis of MM cells treated with CD38 mAb is dosedependent and can occur in the presence of bone marrowderived mesenchymal stem/stromal cells, and in patientderived peripheral blood mononuclear cells (PBMCs)

Preclinical studies showed no adverse effects across several organ systems including liver, spleen, lung, kidney, brain, thymus, prostate, and ovaries in studies up to 6 weeks

People who eat a vegetarian diet, especially strict vegans, need to take extra vitamin B12

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