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Silencing this gene can decrease Bcl-2 expression and increase Bax protein expression, leading to a reduced Bcl-2/Bax ratio, thereby promoting prostate cell apoptosis [38]
As seen with probably all NOX enzymes, there are spatially distinct mechanisms of receptor-mediated NOX1 activation and generation of ROS, confirming that compartmentalisation is necessary for integration of redox-dependent signaling
These results suggested that AP probe-net could suppress xenograft tumor growth in vivo without obvious adverse effects
Sun R, Wang Y, He H, Wan Y, Li L, Sha J, et al
