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MR inhibits Raf and Akt oncogenic pathways, while increasing caspase-9 and the mitochondrial pro-apoptotic protein, Bak [75,76]
As per colorectal cancer, standalone FLX had an IC 50 value of 6.12 M against HT-29 cells with a significant synergetic effect with honeybee venom
Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation
