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doi: 10.1016/j.ghir.2022.101482 129 ArreseMCabreraDKalergisAMFeldsteinAE

Future studies that elucidate its precise mechanism of action in signal transduction cascades could pave the way for development of novel strategies to combat aging and disease

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This intervention increased beneficial bacteria (e.g., Lactobacillus) while suppressing harmful bacteria, upregulated intestinal tight junction proteins (Occludin and Claudin-1) and serum high-density lipoprotein cholesterol (HDL-C) levels, and reduced LPS content alongside TLR4/MyD88/NF-B pathway activation, thereby restoring hepatic histopathology