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This is significant because age-related sleep disruption often involves not just melatonin deficiency but broader circadian gene dysfunction

The impairment of the redox balance, due to an increase in ROS, can potentially trigger apoptosis
[DOI] [PMC free article] [PubMed] [Google Scholar] Kasai H, Fukuda M, Watanabe S, Hayashi-Takagi A, Noguchi J

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