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Toghrayee Z, Montazeri H
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Higher levels of ROS can trigger peripheral and central nervous system hyperexcitability that can lead to hyperalgesia, even without nerve damage or tissue inflammation (Hendrix et al., 2020)
This finding also emphasizes the importance of the biliary excretion as a first step in complex multiorgan pathways involved in glutathione S -conjugate and cysteine S -conjugate metabolism (Dekant et al., 1994)
