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This down-regulation was ameliorated by embelin, in a dose-dependent manner, in comparison with the negative control, and a significant difference was revealed for the 1.2 mg/kg dose of embelin ( Figure 4A )

c , The cytoplasmic C-terminal domain of TMEFF1 (TMEFF1-C) was expressed in bacteria fused to Glutathione-S-transferase (GST)

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Conversely, large prospective cohorts and population-based studies, like for the past population studies, present more nuanced findings, with some reporting no association, possibly due to healthy worker effects, differential exposure misclassification, or lack of detailed shift characteristics