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Generally, GI overproduction of reactive species with oxidative potential can be attributed to both exogenous factors (e.g., smoking, diet, alcohol, and drugs) and endogenous factors (e.g., cellular respiration, respiratory burst, xanthine oxidase, nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, cyclooxygenase (COX), transition metals, nitric oxide synthase (NOS), and myeloperoxidase (MPO), which can collectively lead to pathological conditions 88
It is also unclear whether NAC, as an antioxidant, may alter cancer treatment effectiveness
Among women with chronic pelvic pain, prevalence rates reach 35-50%, while infertile women show rates of 25-50% (Giudice, 2010)
