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10.1042/bj3460001 64 NikiE.NoguchiN.TsuchihashiH.GotohN

2.7 Investigation of antioxidant capability of Se/LDH@PEG The antioxidant efficiency of Se/LDH@PEG was assessed using three distinct free radical scavenging assays (ABTS , DPPH, and OH)

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In terms of the magnitude of fat mass reduction in controlled research settings: Semaglutide (GLP-1 alone): ~1015% body weight Tirzepatide (GLP-1 + GIP): ~1622% body weight Retatrutide (GLP-1 + GIP + Glucagon): ~2429% body weight (Phase 2 data) This stepwise increase with each additional receptor target is a remarkable demonstration of pharmacological synergy and has driven enormous interest in the triple-agonist research space