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10.1016/j.neuro.2010.11.008 33 LesneS

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A study comparing existing anti-SaCas9 and anti-SpCas9 antibodies in serum and vitreous fluid from 13 patients who underwent vitrectomy surgery found that all three serum samples tested positive for SaCas9 and SpCas9, whereas only two vitreous fluid samples were positive for SaCas9, and two others for SpCas9