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doi: 10.1007/s11060-021-03918-0

[15] [17] Unsaturated straight chain fatty acids [edit] Anaerobic desaturation [edit] Many bacteria use the anaerobic pathway for synthesizing unsaturated fatty acids

Elevated intracellular cAMP then drives the following cascade, as characterised in Mel-Ab and B16 melanocyte cell line preparations: MC1R cAMP PKA CREB phosphorylation MITF upregulation tyrosinase expression Picture it this way: MT1 docks at the extracellular binding pocket of MC1R, triggering a conformational shift that couples the receptor to the Gs protein
