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In line with this, only RGY led to elevated levels of mouse C3a (Fig

[10] Initial assessment involves: Detailed medical history, including dietary habits and gastrointestinal symptoms Medication review (certain drugs like metformin and proton pump inhibitors can affect B12 absorption) [20] [21] Family history of pernicious anaemia or autoimmune conditions Physical examination for signs of anaemia or neurological abnormalities Laboratory investigations typically include: Serum vitamin B12 level: The primary test, though interpretation can be complex

ROS are signalling molecules that influence many processes [10], and can initiate inflammatory responses through the activation of various signal transduction pathways and transcription factors, leading to increased gene expression of inflammatory target proteins [14] (Fig
