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Symptoms of a B12 deficiency include: Headaches Fatigue Digestive problems Numbness Trouble walking Nausea Weight loss Irritability Cold hands/ feet Memory loss B12 shots are often prescribed as an effective method to reverse or prevent deficiency because they allow for 100% absorption directly into the tissues

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BMJ 366:l2381

6f), which was consistent with the co-IP and pull-down experiments showing that CFTR PDZ-binding motif enhanced VPS26A-SNX27 interaction (Fig
