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However, to date, oligonucleotide therapeutics are still facing some technological obstacles, such as how to achieve efficient oligonucleotide delivery to target organs or tissues, how to overcome off-target interactions [4952], and how to address the sequence- and chemistry-dependent toxicity and saturation of endogenous RNA processing pathways [53, 54]

RHONDA PATRICK: The safety data is there

The blog notes its research-focused use and the need for additional studies to prove long-term benefits while highlighting its safety and efficacy and highlighting its potential for weight management and general metabolic health

I know you may be thinking, Thats only 2 out of 3 dimensions